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GTIN vs UPC: What's the Difference? [2026 Guide]

If you have ever tried to list a product on Amazon, Google Shopping, or Walmart and been asked for a “GTIN or UPC,” you have run into one of ecommerce’s most confusing pairs of acronyms. The two terms get used as if they are interchangeable, but they are not the same thing, and the relationship between them is simpler than most explanations make it sound. Here is the short version: a UPC is one specific type of GTIN. Get that one sentence and the rest falls into place. This guide explains what a GTIN is, what a UPC is, exactly how they differ, where EAN and ISBN fit in, and what online sellers actually need to do about it.